Brn3a
WebMay 2, 2024 · We have induced retina-specific Cre recombination of our conditional knock-in reporter alleles at the Pou4f1 (Brn3a CKOAP) and Pou4f2 (Brn3b CKOAP) loci using the Pax6α:Cre driver ().When the sister chromosome carries a conventional KO allele, recombination of the conditional allele results in cells lacking both copies of the … WebThis product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved sensitivity …
Brn3a
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WebApr 7, 2024 · f Transcriptional levels of RGC-specific indices, including Brn3a, Brn3c and RBPMS, and programmed cell death-related mRNA, such as caspase 8 and GSDMD, in retinas were detected using qRT-PCR; n > 3. In RIR-induced neuroinflammation, apoptosis is … WebJan 22, 2010 · The transcription factor Brn3a, product of the pou4f1 gene, is expressed in most sensory neurons throughout embryogenesis. Prior work has demonstrated a role for Brn3a in the repression of early neurogenic genes; here we describe a second major role for Brn3a in the specification of sensory subtypes in the trigeminal ganglion (TG). Sensory …
WebDec 14, 2005 · Brn3a is coexpressed extensively with the closely related factor Brn3b in the embryonic retina, and the effects of the loss of Brn3a in retinal development are not severe, suggesting partial redundancy of … WebThe neural crest transcription factor BRN3A is essential for the proliferation and survival of melanoma cells. It is frequently expressed in melanoma but not in normal melanocytes or benign nevi. The mechanisms underlying the aberrant expression of BRN3A are unknown.
WebBRN3A is a class IV POU domain-containing transcription factor highly expressed in the developing sensory nervous system and in cells of the B- and T-lymphocytic lineages. For Research Use Only. Not for use in …
WebOur BRN3A Antibodies can be used in a variety of model species: Human, Mouse, Rat. Use the list below to choose the BRN3A Antibody which is most appropriate for your …
Web7 rows · BRN3A (POU4F1) is a class IV POU domain-containing transcription factor highly expressed in the developing sensory nervous system and in cells of the B- and T … eternal wood robleWeb(A) Gel electrophoresis of Brn3a and GAPDH expression in undifferentiated and differentiated iPS cells. The PCR products obtained after 34 cycles was run on a 3% agarose gel. (B) The relative Brn3a gene expression in undifferentiated and differentiated iPS cells (unpaired t test, p0.0004). Data shown are mean ± SEM of three biological … eternal woods snapshot levelingWebBrn3a, also referred to as POU4F1, RGC-1 or Oct-T1, is a transcription factor highly expressed in the developing peripheral sensory nervous system, cells of the B- and T … fire fire for pc downloadWebJan 22, 2010 · The transcription factor Brn3a, product of the pou4f1 gene, is expressed in most sensory neurons throughout embryogenesis. Prior work has demonstrated a role … eternal word television network rosaryPOU domain, class 4, transcription factor 1 (POU4F1) also known as brain-specific homeobox/POU domain protein 3A (BRN3A), homeobox/POU domain protein RDC-1 or Oct-T1 is a protein that in humans is encoded by the POU4F1 gene. BRN3A (POU4F1) is a class IV POU domain-containing transcription factor hig… eternal world gameWebJun 29, 2024 · Brn3a is a member of the Brn3/Pou4f transcription factor family, which contains key regulators of RGC postmitotic specification. In particular, Brn3a ablation results in the loss of RGCs with small, thick and dense dendritic arbors (‘midget-like’ RGCs), and morphological changes in other RGC subpopulations. fire fire flyleaf official music videoWebDec 20, 2024 · DARC count was defined as the number of fluorescent spots counted by a masked investigator. After sacrifice, their brains were harvested and immunostained for amyloid-beta (Aβ) and phosphorylated tau (pTau). Retinas were immunostained with Brn3a, a retinal ganglion cell (RGC) marker. fire firefly